Selected Publications

Prolonged Dexamethasone Exposure Enhances Zebrafish Lateral-Line Regeneration But Disrupts Mitochondrial Homeostasis and Hair Cell Function

Saettele AL, Wong HC, Kindt KS, Warchol ME, Sheets L.
Journal of the Association for Research in Otolaryngology, 19 October 2022.

Cisplatin exposure acutely disrupts mitochondrial bioenergetics in the zebrafish lateral-line organ

Lee DS, Schrader A, Warchol ME, Sheets L.
Hearing Research. 4 May 2022.

Mechanical overstimulation causes acute injury and synapse loss followed by fast recovery in lateral-line neuromasts of larval zebrafish

Holmgren M, Ravicz ME, Hancock KE, Strelkova O, Kallogjeri D, Indzhykulia AA, Warchol ME, and Sheets L.
Elife. 2021 Oct 19;10:e69264. 

How Zebrafish Can Drive the Future of Genetic-based Hearing and Balance Research

Sheets L, Holmgren M, and Kindt KS.
Journal of the Association for Research in Otolaryngology,  Volume 22pages 215–235, 2021.

Transmission disrupted: modeling auditory synaptopathy in zebrafish

Kindt KS and Sheets L
Front. Cell Dev. Biol., 11 September 2018.

Enlargement of ribbons in zebrafish hair cells increases calcium currents, but disrupts afferent spontaneous activity and timing of stimulus onset

Sheets L, He X, Olt J, Schreck M, Petralia RS, Wang Y, Zhang Q, Nicolson T, Marcotti W, Trapani JG, and Kindt KS.
The Journal of Neuroscience, 2017 Jun 28;37(26):6299-6313.

Ca2+ permeable AMPARs mediate glutamatergic transmission and excitotoxic damage at the hair cell ribbon synapse

Sebe J, Cho S, Sheets L, Rutherford MA, von Gersdorff H, and Raible D
The Journal of Neuroscience, 2017 Jun 21;37(25):6162-6175.

Synaptic ribbons require Ribeye for electron density, synaptic localization and proximity to calcium channels, but not for vesicle recruitment and neurotransmitter release

Lv C, Stewart WJ, Akanyeti O, Frederick C, Zhu J, Santos-Sacchi J, Sheets L, Liao JC, and Zenisek D.
Cell Reports, 2016, Jun 21;15(12):2784-95.

Presynaptic CaV1.3 channels regulate synaptic ribbon size and are required for synaptic maintenance in sensory hair cells.

Sheets L, Kindt KS, Nicolson T.
The Journal of Neuroscience 2012 Nov 28, 32(48):17211-17224.

Ribeye is required for presynaptic CaV1.3a channel localization and afferent innervation of sensory hair cells.

Sheets L, Trapani JG, Mo W, Obholzer N, Nicolson T.
Development 2011 Apr;138(7):1309-19.